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HF®, Nicking, Master Mix, Time-Saver & Other

The Leader in the Discovery and Production of Restriction Enzymes

After nearly 40 years of offering restriction enzymes to the research community, NEB has earned the reputation of being a leader in enzyme technologies. Working continuously to be worthy of that distinction, NEB strives to develop enzymes of the highest purity and unparalleled performance.

NEB scientists continue to improve its portfolio of restriction enzymes, as well as explore their utility in new technologies. As a result, NEB scientists continue to publish scientific papers and to be awarded grants in this area. With the industry’s largest research and development group dedicated to restriction enzymes, we are proud to have been there first: the first to commercialize a recombinant enzyme, the first to introduce a nicking enzyme, and the first to supply a true restriction enzyme master mix. In addition, NEB has an ongoing history of innovation by engineering restriction enzymes with altered specificities and improved performance. Through continued research in these areas, we are committed to driving the innovations that allow us to offer maximum convenience and performance.



Choose Product:

HF®, Nicking, Master Mix, Time-Saver & Other

High-Fidelity (HF®) Restriction Endonucleases

AgeI-HF®

ApoI-HF®

BamHI-HF®

BbsI-HF®

BclI-HF

BmtI-HF®

BsaI-HF®v2

BsiWI-HF®

BsrGI-HF®

BstEII-HF®

BstZ17I-HF®

DraIII-HF®

EagI-HF®

EcoRI-HF®

EcoRV-HF®

HindIII-HF®

KpnI-HF®

MfeI-HF®

MluI-HF®

NcoI-HF®

NheI-HF®

NotI-HF®

NruI-HF®

NsiI-HF®

PstI-HF®

PvuI-HF®

PvuII-HF®

SacI-HF®

SalI-HF®

SbfI-HF®

ScaI-HF®

SpeI-HF®

SphI-HF®

SspI-HF®

StyI-HF®

Homing Endonucleases

I-CeuI

I-SceI

PI-PspI

PI-SceI

Nicking Endonucleases

Nb.BbvCI

Nb.BsmI

Nb.BsrDI

Nb.BssSI

Nb.BtsI

Nt.AlwI

Nt.BbvCI

Nt.BsmAI

Nt.BspQI

Nt.BstNBI

Nt.CviPII

Restriction Enzymes for Epigenetic Analysis

AbaSI

DpnI

DpnII

FspEI

HpaII

LpnPI

McrBC

MspI

MspJI

Time-Saver™ Qualified Restriction Enzymes

AatII

Acc65I

AccI

AciI

AclI

AcuI

AflII

AgeI-HF®

AhdI

AluI

AlwNI

ApaI

ApaLI

ApeKI

ApoI

ApoI-HF®

AscI

AseI

AvaI

AvaII

AvrII

BaeGI

BaeI

BamHI

BamHI-HF®

BbsI

BbsI-HF®

BbvI

BciVI

BclI

BclI-HF

BcoDI

BfuAI

BglI

BglII

BlpI

BmgBI

BmtI-HF®

BpmI

BpuEI

BsaAI

BsaHI

BsaI-HF®v2

BsaWI

BsaXI

BseRI

BsgI

BsiEI

BsiWI

BsiWI-HF®

BslI

BsmAI

BsmBI

BsmI

BsoBI

Bsp1286I

BspCNI

BspEI

BspHI

BspQI

BsrBI

BsrDI

BsrGI

BsrI

BssHII

BstBI

BstEII

BstEII-HF®

BstNI

BstUI

BstXI

BstYI

BstZ17I

BstZ17I-HF®

Bsu36I

BtgI

BtsCI

Cac8I

ClaI

CspCI

CviAII

CviQI

DdeI

DpnI

DpnII

DraI

DraIII-HF®

DrdI

EagI

EagI-HF®

EarI

Eco53kI

EcoNI

EcoO109I

EcoP15I

EcoRI

EcoRI-HF®

EcoRV

EcoRV-HF®

Esp3I

Fnu4HI

FseI

FspI

HaeIII

HhaI

HincII

HindIII-HF®

HinfI

HinP1I

HpaII

HphI

Hpy166II

HpyAV

HpyCH4IV

HpyCH4V

KpnI

KpnI-HF®

MboI

MfeI-HF®

MluCI

MluI

MlyI

MmeI

MnlI

MseI

MslI

MspA1I

MspI

MwoI

NciI

NcoI

NcoI-HF®

NdeI

NgoMIV

NheI

NheI-HF®

NlaIII

NotI

NotI-HF®

NruI

NsiI

NspI

PacI

PaeR7I

PflFI

PflMI

PmeI

PmlI

PpuMI

PshAI

PstI

PstI-HF®

PvuI

PvuI-HF®

PvuII

PvuII-HF®

RsaI

SacI

SacI-HF®

SacII

SalI

SalI-HF®

SapI

SbfI

SbfI-HF®

ScaI-HF®

SfiI

SfoI

SmaI

SpeI

SpeI-HF®

SphI-HF®

SspI-HF®

StuI

StyD4I

StyI

StyI-HF®

SwaI

TaqαI

TfiI

TseI

TspMI

TspRI

Tth111I

XbaI

XhoI

XmaI

XmnI

High-Fidelity (HF®) Restriction Endonucleases

AgeI-HF®

ApoI-HF®

BamHI-HF®

BbsI-HF®

BclI-HF

BmtI-HF®

BsaI-HF®v2

BsiWI-HF®

BsrGI-HF®

BstEII-HF®

BstZ17I-HF®

DraIII-HF®

EagI-HF®

EcoRI-HF®

EcoRV-HF®

HindIII-HF®

KpnI-HF®

MfeI-HF®

MluI-HF®

NcoI-HF®

NheI-HF®

NotI-HF®

NruI-HF®

NsiI-HF®

PstI-HF®

PvuI-HF®

PvuII-HF®

SacI-HF®

SalI-HF®

SbfI-HF®

ScaI-HF®

SpeI-HF®

SphI-HF®

SspI-HF®

StyI-HF®

Homing Endonucleases

I-CeuI

I-SceI

PI-PspI

PI-SceI

Nicking Endonucleases

Nb.BbvCI

Nb.BsmI

Nb.BsrDI

Nb.BssSI

Nb.BtsI

Nt.AlwI

Nt.BbvCI

Nt.BsmAI

Nt.BspQI

Nt.BstNBI

Nt.CviPII

Restriction Enzymes for Epigenetic Analysis

AbaSI

DpnI

DpnII

FspEI

HpaII

LpnPI

McrBC

MspI

MspJI

Time-Saver™ Qualified Restriction Enzymes

AatII

Acc65I

AccI

AciI

AclI

AcuI

AflII

AgeI-HF®

AhdI

AluI

AlwNI

ApaI

ApaLI

ApeKI

ApoI

ApoI-HF®

AscI

AseI

AvaI

AvaII

AvrII

BaeGI

BaeI

BamHI

BamHI-HF®

BbsI

BbsI-HF®

BbvI

BciVI

BclI

BclI-HF

BcoDI

BfuAI

BglI

BglII

BlpI

BmgBI

BmtI-HF®

BpmI

BpuEI

BsaAI

BsaHI

BsaI-HF®v2

BsaWI

BsaXI

BseRI

BsgI

BsiEI

BsiWI

BsiWI-HF®

BslI

BsmAI

BsmBI

BsmI

BsoBI

Bsp1286I

BspCNI

BspEI

BspHI

BspQI

BsrBI

BsrDI

BsrGI

BsrI

BssHII

BstBI

BstEII

BstEII-HF®

BstNI

BstUI

BstXI

BstYI

BstZ17I

BstZ17I-HF®

Bsu36I

BtgI

BtsCI

Cac8I

ClaI

CspCI

CviAII

CviQI

DdeI

DpnI

DpnII

DraI

DraIII-HF®

DrdI

EagI

EagI-HF®

EarI

Eco53kI

EcoNI

EcoO109I

EcoP15I

EcoRI

EcoRI-HF®

EcoRV

EcoRV-HF®

Esp3I

Fnu4HI

FseI

FspI

HaeIII

HhaI

HincII

HindIII-HF®

HinfI

HinP1I

HpaII

HphI

Hpy166II

HpyAV

HpyCH4IV

HpyCH4V

KpnI

KpnI-HF®

MboI

MfeI-HF®

MluCI

MluI

MlyI

MmeI

MnlI

MseI

MslI

MspA1I

MspI

MwoI

NciI

NcoI

NcoI-HF®

NdeI

NgoMIV

NheI

NheI-HF®

NlaIII

NotI

NotI-HF®

NruI

NsiI

NspI

PacI

PaeR7I

PflFI

PflMI

PmeI

PmlI

PpuMI

PshAI

PstI

PstI-HF®

PvuI

PvuI-HF®

PvuII

PvuII-HF®

RsaI

SacI

SacI-HF®

SacII

SalI

SalI-HF®

SapI

SbfI

SbfI-HF®

ScaI-HF®

SfiI

SfoI

SmaI

SpeI

SpeI-HF®

SphI-HF®

SspI-HF®

StuI

StyD4I

StyI

StyI-HF®

SwaI

TaqαI

TfiI

TseI

TspMI

TspRI

Tth111I

XbaI

XhoI

XmaI

XmnI