New England Biolabs is working diligently to ensure we keep our employees and their families safe, while maintaining our business continuity. Despite a "Stay At Home" advisory being put in place in Massachusetts, USA, we are deemed an essential business, and our manufacturing and distribution teams continue to be fully operational. We are continuing to work with our suppliers and distribution partners to ensure uninterrupted access to our products and technical support.

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Having supplied restriction enzymes to the research community for over 40 years, NEB has earned the reputation of being the leader in enzyme technologies.  Working continuously to be worthy of that distinction, NEB strives to develop enzyme of the highest purity and unparalleled quality. 

  • Time-Saver™ qualified for digestion in 5-15 minutes
  • 100% activity in CutSmart® Buffer (over 210 enzymes are available in the same buffer) allowing for easier double digests
  • High Fidelity (HF®) version available (NEB #R3642) supplied with CutSmart Buffer
Learn more about how this product is being used in the Product Citation Tool
Catalog # Concentration Size
R0642S 10,000 units/ml 500 units
R0642L 10,000 units/ml 2,500 units
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