5-methyl-dCTP

Cytosine modification at carbon 5 (C5) represents an important epigenetic modification. It is also believed to be the starting substrate for the Ten-Eleven Translocation (TET) family of enzymes and their associated oxidation pathways.

  • 5-methyl-dCTP (2'-deoxy-5-methylcytidine 5'-triphosphate) offers the ability to enzymatically make defined, fully methylated, cytosine-substituted DNA, which can be used for a variety of biochemical and cellular applications
  • 5-methyl-dCTP is supplied as a 10 mM solution at pH 7. Nucleotide concentration is determined by measurements of absorbance at 260 nm.
Catalog # Concentration Size
N0356S 10 mM 1 µmol
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    Product Categories:
    Nucleotide Solutions Products
    Applications:
    Histones & Nucleosome Assembly,
    DNA Methylation Analysis,
    DNA Sequencing
    ,
    PCR
    ,
    RT-PCR & cDNA Synthesis
    ,
    PCR
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