Histone H3.1 Human, Recombinant
cloned at NEB recombinant

Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Histone H3.1 is an H3 variant that has thus far only been found in mammals, is replication dependent and is associated with gene activation and gene silencing.

  • Highly pure, recombinant protein
  • Mass confirmed by ESI-TOF MS
  • Tested for exonuclease, endonuclease and protease contamination
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Catalog # Concentration Size
M2503S 1 mg/ml 100 µg
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  • Product Information

    Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. It is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.

    Histone H3.1, an H3 variant that has thus far only been found in mammals, is replication dependent and is associated with gene activation and gene silencing.

    Protein Sequence: ARTKQ TARKS TGGKA PRKQL ATKAA RKSAP ATGGV KKPHR YRPGT VALRE IRRYQ KSTEL LIRKL PFQRL VREIA QDFKT DLRFQ SSAVM ALQEA CEAYL VGLFE DTNLC AIHAK RVTIM PKDIQ LARRI RGERA (Genbank accession number: AAN10051)

    SDS-PAGE analysis of Histone H3.1 Human, Recombinant
    SDS-PAGE analysis of Histone H3.1 Human, Recombinant
    Lane 1: NEB Unstained Protein Marker, Broad Range (NEB #P7702), Lane 2 thru 6: 0.5, 1.0, 2.0, 5.0, 10.0 µg Histone H3.1 Human, Recombinant.

     

    ESI-TOF Mass Spectrometry Analysis of Histone H3.1 Human, Recombinant
    ESI-TOF Analysis of Histone H3.1 Human, Recombinant

    Product Source

    An E.coli strain that carries a plasmid encoding the cloned human histone H3.1 gene, HIST1H3A or H3FA. (Genbank accession number: AF531274)
    This product is related to the following categories:
    Histones Products
    This product can be used in the following applications:
    Histones & Nucleosome Assembly
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