Histone H10 Human, Recombinant
Histone H10 is a non-replication-dependent histone that is highly expressed in terminally differentiated cells (3).
- Highly pure, recombinant protein
- Identity confirmed using Edman Degradation to sequence intact protein
- Mass confirmed by ESI-TOF MS
- Tested for exonuclease, endonuclease and protease contamination
Histone H1 acts on the linker region of polynucleosome DNA to condense the chromatin into structures of ~30 nm (1). It is not necessary for octamer or nucleosome core particle formation. Eight different Histone H1 proteins have been identified in the human genome (2). Histone H10 is a non replication-dependent histone that is highly expressed in cells that have terminally differentiated (3).
TENST SAPAA KPKRA KASKK STDHP KYSDM IVAAI QAEKN RAGSS RQSIQ KYIKS HYKVG ENADS QIKLS IKRLV TTGVL KQTKG VGASG SFRLA KSDEP KKSVA FKKTK KEIKK VATPK KASKP KKAAS KAPTK KPKAT PVKKA KKKLA ATPKK AKKPK TVKAK PVKAS KPKKA KPVKP KAKSS AKRAG KKK (Genbank accession number: P07305)
Product SourceAn E. coli strain that carries a plasmid encoding the human histone H1 gene, H1F0 or H1FV. (Genbank accession number: X03473)
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