Thermolabile Exonuclease I
icon_recomb icon_neb3_1 icon_incTemp37 heat inactivation

Interested in a 5-minute protocol? Try out the Exo-CIP Rapid PCR Cleanup Kit (NEB #E1050)

  • DNA specific exonuclease
  • Catalyzes the removal of nucleotides from linear single-stranded DNA in the 3' to 5' direction
  • Unlike Exonuclease I (NEB #M0293), Thermolabile Exonuclease I can be heat inactivated at 80°C in 1 minute 

Thermolabile Exonuclease I is ideal for:

  • Removal of single-stranded primers in PCR reactions prior to DNA sequencing or SNP analysis
  • Removal of single-stranded primers for nested PCR reactions
  • Removal of linear single-stranded DNA, leaving behind double-stranded DNA in the sample

Request a copy of our Choosing the Right Exonuclease poster.

Catalog # Concentration Size
M0568S 20,000 units/ml 3,000 units
M0568L 20,000 units/ml 15,000 units
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