Thermostable RNase H
icon_recomb icon_NEBU incubation temp icon_HI_no

Thermostable RNase H specifically recognizes and cleaves the phosphodiester bonds of an RNA strand in an RNA-DNA hybrid while leaving the DNA strand intact. This thermostable nuclease exhibits the same enzymatic properties as E. coli RNase H, but is active at much higher temperatures.

  • Recombinant enzyme supplied with 10X Reaction Buffer
  • Does not digest single or double-stranded DNA
  • Active and stable above 37°C over a broad temperature range, with activity increasing with temperature
  • Requires magnesium chloride for activity
  • Inactivated with proteinase K treatment or addition of excess EDTA
Learn more about how this product is being used in the Product Citation Tool
2019-20_Catalog_Promo_0519
Catalog # Concentration Size
M0523S 5000 units/ml 250 units
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