Shrimp Alkaline Phosphatase (rSAP)
recombinant neb31 37 65 Heat

We are excited to announce that we are in the process of switching all reaction buffers to be BSA-free. Beginning April 2021, we will be gradually transitioning to buffers containing Recombinant Albumin (rAlbumin) for restriction enzymes and some DNA modifying enzymes. All information on the website has been updated to reflect this change. Find more details at www.neb.com/BSA-free.

Shrimp Alkaline Phosphatase (rSAP) is a heat labile alkaline phosphatase purified from a recombinant source.

  • Rapid and irreversible heat inactivation eliminates unwanted activity
  • Improved storage stability versus native enzyme
  • Faster reaction setup (no supplemental additives like zinc required)
  • Flexible reaction conditions (active in any restriction enzyme buffer, no clean-up required)
  • Less enzyme required (high specific activity), resulting in a lower cost per reaction
  • No need for multiple phosphatases (rSAP removes 5´- and 3´- phosphates from DNA, RNA and dNTPs )
  • Active on unincorporated dNTPs in PCR products - improves DNA sequencing and SNP analysis
  • Recombinant for purity, consistency and value
Note: See also Exo-CIP™ Rapid PCR Cleanup Kit (NEB #E1050).
Catalog # Concentration Size
M0371S 1,000 units/ml 500 units
M0371L 1,000 units/ml 2,500 units
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