Tth Endonuclease IV
icon_recomb icon_NEBU incubation temp icon_HI_no

The large size of this product has been discontinued.

  • Thermostable DNA AP endonuclease
  • Catalyzes the cleavage of DNA phosphodiester backbone at AP sites via hydrolysis, leaving a 1 nucleotide gap with 3'-hydroxyl and 5' deoxyribose phosphate (dRP) termini
  • Also has 3'-diesterase activity which can remove 3' phosphate, 3'-α, β-unsaturated aldehyde, phosphoglycoaldehyde, and other 3' blocking groups
  • Heat inactivation not possible
Learn more about how this product is being used in the Product Citation Tool
Catalog # Concentration Size
M0294S 10,000 units/ml 500 units
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