APE 1
icon_cloned icon_recomb icon_NEB4 icon_incTemp37 icon_HI_65

  • Apurinic/apyrimidinic Endonuclease 1
  • DNA AP endonuclease that catalyzes the cleavage of DNA phosphodiester backbone at AP sites via hydrolysis leaving a 1 nucleotide gap with 3'-hydroxyl and 5' deoxyribose phosphate (dRP) termini
  • APE 1 has also been reported to have DNA 3'-diesterase, 3' to 5' exonuclease, and RNase H activities
  • Also known as HAP1 or Ref-1
Learn more about how this product is being used in the Product Citation Tool
2019-20_Catalog_Promo_0519
Catalog # Concentration Size
M0282S 10,000 units/ml 1,000 units
M0282L 10,000 units/ml 5,000 units
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