Fpg
icon_recomb icon_NEB1 icon_incTemp37 icon_HI_60 bsa

  • Formamidopyrimidine DNA Glycosylase
  • Bifunctional DNA glycosylase with DNA N-glycosylase and AP lyase activities
  • N-glycosylase activity releases damaged purines, including 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 8-oxo-7,8-dihydroguanine (8oxoG), generating an AP site. The AP lyase activity cleaves an AP site, via β and δ-elimination, creating a 1 nucleotide DNA gap with 5' and 3' phosphate termini.

 

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Catalog # Concentration Size
M0240S 8,000 units/ml 500 units
M0240L 8,000 units/ml 2,500 units
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