NEBNext Direct® BRCA1/BRCA2 Panel

This product was discontinued on 12/31/20. In place of E6627, the content can be ordered as NEBNext Direct Custom Ready Panels.

  • Catalog # E6627 was discontinued on December 31, 2020 ;

NEBNext Direct employs a unique hybridization-based enrichment workflow that hybridizes baits directly to genomic DNA, without the need for upfront library preparation. The BRCA1/BRCA2 panel demonstrates extremely high specificity and unmatched coverage uniformity across a wide range of DNA inputs, allowing highly sensitive calling of germline and somatic variants while maximizing sequencer efficiency. 

  • Generate full (100%) coverage of all protein coding regions in BRCA1 and BRCA2 genes
  • Obtain highly uniform sequencing across exon targets- 100% of base pairs in panel have coverage greater than 20% of the mean target coverage
  • Maximize efficiency with a 1-day workflow that combines highly specific enrichment with library preparation
  • Produce high depths of target coverage across a wide range of DNA input amounts for germline and somatic variant calling
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