NEBNext® rRNA Depletion Kit (Human/Mouse/Rat)

Note that RNA Sample Purification beads are not included in this kit. If beads are required, we recommend ordering the NEBNext rRNA Depletion Kit with Sample Purification Beads (NEB #E6350).

An updated version of this kit (NEB #E7400) is available for superior performance.

Ribosomal RNAs (rRNAs) are extremely abundant, constituting 80–90% of total RNA. Efficient removal of rRNA is critical to enable cost-effective sequencing of RNA samples, but this can be especially challenging with low quality RNA (e.g. FFPE RNA) and with low input amounts. The NEBNext rRNA Depletion kit employs the efficient RNase H method, as well as complete probe tiling of rRNA, thereby ensuring that even degraded rRNA is hybridized and subsequently removed.

  • Suitable for low-quality (e.g. FFPE) or high-quality RNA
  • Compatible with a broad range of input amounts: 10 ng - 1 μg
  • Fast workflow: 2 hours, with less than 10 minutes hands-on time
Catalog # Concentration Size
E6310S Not Applicable 6 reactions
E6310L Not Applicable 24 reactions
E6310X Not Applicable 96 reactions
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