HomeFAQsCan the Monarch Genomic DNA Purification Kit (NEB #T3010) be used for isolating cfDNA?
FAQ: Can the Monarch Genomic DNA Purification Kit (NEB #T3010)be used for isolating cfDNA?
We do not recommend this kit for isolation of cfDNA. cfDNA contains small DNA fragments, and the binding chemistry in this kit is not optimized for small fragments. Additionally, the workflow is not optimized to process large volumes of starting materials, which is often necessary when isolating cfDNA.