FAQ: What is the target specificity of yDcpS?

yDcpS has decapping activity on most guanosine-based caps, but no activity on A, C, or U caps. Cap0 and Cap1 structures are both decapped by yDcpS. Importantly, yDcpS does not remove desthiobiotin GTP or , m2,2,7G caps.

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yDcpS