FAQ: What advantages does WarmStart® RTx provide?

Similar to use of hot-start DNA polymerases, a warm-start reverse transcriptase enables consistent performance in amplification reactions. With the WarmStart® property, any RT-LAMP reaction using either WarmStart RTx or Bst 2.0 WarmStart DNA Polymerase (NEB #M0538) can be set up at room temperature, without off-target amplification. This control provides a greater degree of specificity to RNA detection and amplification reactions, and enables flexibility in high-throughput or ice-free setup.